The grandma is the main antagonist of Cookie Clicker Classic and the 1.0 Update, and the second building you can purchase with an initial cost of 100 cookies. She produces cookies at a base rate of 1 cookie per second.
Unlike the Cursor and Farm, grandmas progress with later buildings very well with the grandma type upgrades, most of which double its efficiency but require 15 or more of a superior building to purchase, and sometimes can be quite expensive, up to 3.55 sextillion cookies for Binary grandmas. After all upgrades, each grandma has a CpS of 104857.6 cookies per second herself, not counting the bonuses from One mind, Communal Brainsweep, and Elder Pact.
Once you have unlocked 7 grandmas, you unlock the Bingo Center/Research Facility, which (as of 1.036) is currently the only upgrade to make a building four times as efficient, although its price of 1 quadrillion cookies means it'll be a while until it's worth the cost. This will unlock a new upgrade after 30 minutes (research only starting once the last item researched is purchased), including five multiplier upgrades, one upgrade to double grandma efficiency, and three upgrades to greatly increase grandma output but start the Grandmapocalypse.
Appease the grandmatriarchs at least 5 times. "our mind outlives the universe"
Declare a covenant with the grandmatriarchs. "we have fed"
Forwards from grandma
Own 1 grandma
Grandmas are twice as efficient. "RE:RE:thought you'd get a kick out of this ;))"
Steel-plated rolling pins
Own 5 grandmas
Grandmas are twice as efficient. "Just what you kneaded."
Own 25 grandmas
Grandmas are twice as efficient. "squish"
Own 50 grandmas
Grandmas are twice as efficient. "Gets me going."
Own 100 grandmas
Grandmas are twice as efficient. "Oh... so THAT's what I've been baking."
Own 150 grandmas
Grandmas are twice as efficient. "Counter-intuitively, grandmas have the uncanny ability to become more powerful the older they get."
Own 200 grandmas
Grandmas are twice as efficient. "Complete with flame decals and a little horn that goes "toot"."
Own 250 grandmas
Grandmas are twice as efficient. "It might be a classic tale of bad parenting, but let's see where grandma is going with this."
Own 300 grandmas
Grandmas are twice as efficient. "Extremely unsettling, and somehow even worse than the regular kind."
Timeproof hair dyes
Own 350 grandmas
Grandmas are twice as efficient. "Why do they always have those strange wispy pink dos? What do they know about candy floss that we don't?"
Own 400 grandmas
Grandmas are twice as efficient. "Apparently these ladies are much more amiable if you take the time to learn their strange, ancient customs, which seem to involve saying "please" and "thank you" and staring at the sun with bulging eyes while muttering eldritch curses under your breath."
Own 450 grandmas
Grandmas are twice as efficient. "Genetic testing shows that most of your grandmas are infected with a strange degenerative disease that only seems to further their powers; the more time passes, the older they get. This should concern you."
Own 500 grandmas
Grandmas are twice as efficient. "In an extensive double-blind study (sample size: 12 millions), your researchers have found evidence that grandmas are up to twice as productive if you just come by and say hi once in a while. It's nice to check up on your grans! (Do not under any circumstances ingest any tea or tea-like substances the grandmas may offer you.)."
15 farms and 1 grandma owned
Grandmas are twice as efficient. Farms gain +1% CpS per grandma. "A nice farmer to grow more cookies."
15 mines and 1 grandma owned
Grandmas are twice as efficient. Mines gain +1% CpS per 2 grandmas. "A nice miner to dig more cookies."
15 factories and 1 grandma owned
Grandmas are twice as efficient. Factories gain +1% CpS per 3 grandmas. "A nice worker to manufacture more cookies."
15 banks and 1 grandma owned
Grandmas are twice as efficient. Banks gain +1% CpS per 4 grandmas "A nice banker to cash in more cookies"
15 temples and 1 grandma owned
Grandmas are twice as efficient. Temples gain +1% CpS per 5 grandmas. "A nice priestess to praise the great Baker in the sky."
15 wizard towers and 1 grandma owned
Grandmas are twice as efficient. Wizard towers gain +1% CpS per 6 grandmas. "A nice witch to cast a zip, and a zoop, and poof! Cookies."
15 shipments and 1 grandma owned
Grandmas are twice as efficient. Shipments gain +1% CpS per 7 grandmas. "A nice thing to... uh... cookies."
15 alchemy labs and 1 grandma owned
Grandmas are twice as efficient. Alchemy labs gain +1% CpS per 8 grandmas. "A nice golden grandma to convert into more cookies."
15 portals and 1 grandma owned
Grandmas are twice as efficient. Portals gain +1% CpS per 9 grandmas. "a NiCe GrAnDmA tO bA##########"
15 time machines and 1 grandma owned
Grandmas are twice as efficient. Time machines gain +1% CpS per 10 grandmas. "A nice grandma's nice grandma to bake double the cookies."
15 antimatter condensers and 1 grandma owned
Grandmas are twice as efficient. Antimatter condensers gain +1% CpS per 11 grandmas. "A mean antigrandma to vomit more cookies. (Do not put in contact with normal grandmas; loss of matter may occur.)"
15 prisms and 1 grandma owned
Grandmas are twice as efficient. Prisms gain +1% CpS per 12 grandmas. "A luminous grandma to sparkle into cookies."
15 chancemakers and 1 grandma owned
Grandmas are twice as efficient. Chancemakers gain +1% CpS per 13 grandmas. "A fortunate grandma that always seems to find more cookies."
15 fractal engines and 1 grandma owned
Grandmas are twice as efficient. Fractal engines gain +1% CpS per 14 grandmas. "A fractal grandma to make more grandmas to make more cookies."
15 idleverses and 1 grandma owned
Grandmas are twice as efficient. Idleverses gain +1% CpS per 16 grandmas. "A different grandma to bake something else."
Grandma's different appearances
Purchasing "A festive hat" or evolving Santa
2,525 × 3S
Grandmas are twice as productive. Cost scales with Santa level. "This list contains every unholy deed perpetuated by grandmakind. He won't be checking this one twice. Once. Once is enough."
Random fortune from news ticker
Grandmas are 7% more efficient and 7% cheaper. "A wrinkle is a crack in a mundane facade."
The Bingo Center/Research Facility can also unlock new upgrades for grandmas. Although these upgrades can make grandmas more powerful, they would unlock the Grandmapocalypse as well. The following is a list of all upgrades for Grandma, unlocked in the Bingo Center/Research Facility. Once the Bingo Center is purchased, the first research project will be completed 30 minutes later. Once a research project is completed, research is halted until the resulting upgrade is purchased, which starts the 30-minute timer for the next project.
Changes from one stage to another can be obtained by the One Mind, Communal Brainsweep and Elder Pact upgrade. Once they're appeased, the background will change back to normal temporarily. When the Grandmatriarchs are appeased, the store icon will change back to normal.
Store Icon Changes
Since version 1.0393, the store icon for grandmas will change from the regular version to different ones, depending on the state of the Grandmapocalypse.
The outfit worn by bunny grandmas during Easter may be a reference to the 2001 film Donnie Darko.