The Shipment is the eighth most expensive building in the game, initially costing 5.1 billion cookies. Each shipment produces 260,000 cookies per second by bringing in fresh cookies from the cookie planet.
Shipments are twice as efficient. "If you removed your space helmet, you could probably smell it! (Note : don't do that.)"
Own 5 shipments
Shipments are twice as efficient. "By using these as shortcuts, your ships can travel much faster."
Own 25 shipments
Shipments are twice as efficient. "Come back soon!"
Own 50 shipments
Shipments are twice as efficient. "To boldly bake."
Own 100 shipments
Shipments are twice as efficient. "My god. It's full of chocolate bars."
Own 150 shipments
Shipments are twice as efficient. "Built to last, this humongous spacecraft will surely deliver your cookies to the deep ends of space, one day."
Own 200 shipments
Shipments are twice as efficient. "You've found a way to apply your knowledge of cosmic technology to slightly more local endeavors; this gigantic sphere of meta-materials, wrapping the solar system, is sure to kick your baking abilities up a notch."
The final frontier
Own 250 shipments
Shipments are twice as efficient. "It's been a long road, getting from there to here. It's all worth it though - the sights are lovely and the oil prices slightly more reasonable."
Own 300 shipments
Shipments are twice as efficient. "Your ships are now fitted with completely robotic crews! It's crazy how much money you save when you don't have to compensate the families of those lost in space."
Restaurants at the end of the universe
Own 350 shipments
Shipments are twice as efficient. "Since the universe is spatially infinite, and therefore can be construed to have infinite ends, you've opened an infinite chain of restaurants where your space truckers can rest and partake in some home-brand cookie-based meals."
Own 400 shipments
Shipments are twice as efficient. "You've managed to chart a language that can be understood by any sentient species in the galaxy; its exciting vocabulary contains over 56 trillion words that sound and look like sparkly burps, forming intricate sentences that usually translate to something like "give us your cookies, or else"."
You need at least 15 shipments to purchase the "Cosmic Grandmas" upgrade.
The fact that shipments "Brings in fresh cookies from the cookie planet" seems to suggest that Cookie Clicker takes place in a universe where planets are made of cookie dough. This is reinforced by mines suggesting the Cookie Clicker planet itself is made of cookies.
However, portals are doorways the 'Cookieverse' meaning that it could just be set in the far future.
The mines might have a formula that turns dirt into cookie dough and chocolate, similar to Alchemy Lab.
The flavor text from the Warp Drive achievement,"To boldly bake" is a reference to Star Trek, in which the mission of the U.S.S. Enterprise is "to boldly go where no man has gone before."
The flavor text for the Chocolate monoliths achievement, "It's full of chocolate bars" is a reference to 2001: A Space Odyssey, in which the protagonist says "It's full of stars!"
A generation ship or generationg starship is a hypothetical type of interstellar ark starship that travels across great distances between stars at a speed slower than the speed of light.
The achievement titled "Type II Civilization" refers to the Kardasheve Scale, a measurement of how advanced an alien race is.
The fact that most upgrades consist of 51 is a reference to Planet 51, by SEGA.
The final upgrade quote "It's been a long road, getting from there to here" seems to reference the Star Trek:Enterprise theme song Faith of the heart
The upgrade "Restaurants at the end of the universe" is a reference to the book The Hitchhiker's Guide to the Galaxy.