Once you're at the point where there's not much you can do but wait and click cookies/popups to earn enough to buy 200 of everything, is it ever efficient to sell all of your medium buildings?
For example, let's say you have 280 cursors, 250 grandmas, 200 each of farms, factories, mines, and shipments, and 150 or less of everything else. Is it worth it to sell all of the farms, factories, mines, and shipments, or would that be too much of a waste?
(For those who don't want to check the page for it, selling a building gives you half of its current price.)